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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPA2
All Species:
18.18
Human Site:
S140
Identified Species:
36.36
UniProt:
P15927
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15927
NP_002937.1
270
29247
S140
R
S
F
Q
N
K
K
S
L
V
A
F
K
I
M
Chimpanzee
Pan troglodytes
XP_513251
401
43665
S271
R
S
F
Q
N
K
K
S
L
V
A
F
K
I
M
Rhesus Macaque
Macaca mulatta
XP_001088106
261
28832
L140
C
P
T
G
T
K
T
L
E
V
L
K
I
H
V
Dog
Lupus familis
XP_544465
368
39870
S238
R
S
F
Q
N
K
K
S
L
V
A
F
K
I
M
Cat
Felis silvestris
Mouse
Mus musculus
Q62193
270
29700
S140
R
S
F
Q
N
K
K
S
L
V
A
F
K
I
I
Rat
Rattus norvegicus
Q63528
270
29327
S140
R
S
F
Q
N
K
K
S
L
V
A
F
K
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518418
244
26194
H133
T
Y
V
K
V
A
G
H
L
R
S
F
Q
N
R
Chicken
Gallus gallus
NP_001026063
267
28845
I144
K
S
L
V
A
F
K
I
M
P
L
E
N
M
N
Frog
Xenopus laevis
NP_001090609
274
29360
V140
S
F
Q
N
K
K
S
V
V
A
F
K
I
A
P
Zebra Danio
Brachydanio rerio
NP_571786
272
29609
D147
F
S
V
R
V
L
E
D
M
N
E
V
T
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330767
282
31111
Q147
R
V
F
Q
D
V
K
Q
L
V
A
F
S
V
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P26754
273
29918
E142
K
V
F
G
A
L
K
E
F
G
G
K
K
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.5
42.2
67.6
N.A.
87.4
88.8
N.A.
65.5
69.2
64.2
56.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
67.3
60
70.9
N.A.
92.2
94
N.A.
75.9
81.8
79.1
72
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
13.3
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
33.3
33.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
31.2
N.A.
N.A.
N.A.
21.9
N.A.
Protein Similarity:
52.1
N.A.
N.A.
N.A.
43.2
N.A.
P-Site Identity:
53.3
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
9
0
0
0
9
50
0
0
9
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
9
9
9
0
9
9
0
0
0
% E
% Phe:
9
9
59
0
0
9
0
0
9
0
9
59
0
0
0
% F
% Gly:
0
0
0
17
0
0
9
0
0
9
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
9
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
17
42
25
% I
% Lys:
17
0
0
9
9
59
67
0
0
0
0
25
50
0
0
% K
% Leu:
0
0
9
0
0
17
0
9
59
0
17
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
17
0
0
0
0
9
25
% M
% Asn:
0
0
0
9
42
0
0
0
0
9
0
0
9
17
9
% N
% Pro:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
9
% P
% Gln:
0
0
9
50
0
0
0
9
0
0
0
0
9
0
0
% Q
% Arg:
50
0
0
9
0
0
0
0
0
9
0
0
0
0
17
% R
% Ser:
9
59
0
0
0
0
9
42
0
0
9
0
9
9
0
% S
% Thr:
9
0
9
0
9
0
9
0
0
0
0
0
9
0
0
% T
% Val:
0
17
17
9
17
9
0
9
9
59
0
9
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _